Therapeutic potential of purine analogue
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S. A. Johnson; W. Thomas
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Article
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2000
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John Wiley and Sons
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English
โ 94 KB
๐ 2 views
The main purine analogues with activity against lymphoid malignancies are fludarabine, cladribine and pentostatin, all of which are active against slowly proliferating cells through their inhibition of DNA repair and therefore have significant synergistic activity with cytotoxic agents which cause D