Therapeutic potential of Kupffer cells in prevention of liver metastases outgrowth
โ Scribed by Gerben J. van der Bij; Steven J. Oosterling; Sybren Meijer; Robert H.J. Beelen; Marjolein van Egmond
- Book ID
- 116569076
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 271 KB
- Volume
- 210
- Category
- Article
- ISSN
- 0171-2985
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๐ SIMILAR VOLUMES
It is well recognized that consumption of alcohol leads to liver disease in a dose-dependent manner; however, the exact mechanisms remain unclear. Hypoxia subsequent to a hypermetabolic state may be involved: therefore, when it was observed recently that inactivation of Kupffer cells prevented stimu
Tumour cells from a squamous carcinoma (approximately 2.5 X 10(5)) were injected intraportally into a syngeneic strain of rats to produce liver metastases 14 days later. Kupffer cells were stimulated by Corynebacterium parvum (7 mg or 1 mg i.v.) and zymosan (10 mg intraportally). Kupffer cell activi