## Abstract ## BACKGROUND Drug delivery to the central nervous system (CNS) remains a real challenge for neurosurgeons and neurologists, because many molecules cannot cross the blood‐brain barrier (BBB). In recent years, solid polymeric materials have been implanted into animal and human brains ei
✦ LIBER ✦
Therapeutic efficacy of 5-fluorouracil-loaded microspheres on rat glioma: a magnetic resonance imaging study
✍ Scribed by L. Lemaire; V.-G. Roullin; F. Franconi; M.-C. Venier-Julienne; P. Menei; P. Jallet; J.-J. Le Jeune; J.-P. Benoit
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 204 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.720
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## Abstract T~1~‐weighted magnetic resonance imaging (MRI) was used to evaluate the potential interest of a new Gd‐based contrast agent, termed P760, to characterize brain tumor heterogeneity and vascularization and to delineate regions containing permeable vessels. The C6 rat glioma model was used