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Therapeutic effects of intrabone and systemic mesenchymal stem cell cytotherapy on myeloma bone disease and tumor growth

✍ Scribed by Xin Li; Wen Ling; Sharmin Khan; Shmuel Yaccoby


Book ID
112118131
Publisher
American Society for Bone and Mineral Research
Year
2012
Tongue
English
Weight
626 KB
Volume
27
Category
Article
ISSN
0884-0431

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## Abstract During the last decade, a central role for insulin‐like growth factor 1 (IGF‐1) in the pathophysiology of multiple myeloma (MM) has been well established. IGF‐I provided by the tumor–microenvironment interaction may directly and indirectly facilitate the migration, survival and expansio