Therapeutic effects of 6-azauridine-triacetate in psoriasis

✍ Scribed by Slavík, M. ;Elis, J. ;Rašková, H. ;Gutová, M. ;Duchková, M. ;Kubíková, M. ;Seyček, V.

• Book ID: 104768886
• Publisher: Springer-Verlag
• Year: 1970
• Weight: 666 KB
• Volume: 2
• Category: Article
• ISSN: 0369-9498
• DOI: 10.1007/bf00420718

✦ Synopsis

In a controlled clinical trial 6-azauridinetriacetate, a drug that inhibits the synthesis of pyrimidine "de novo", had a therapeutic effect in psoriasis. The general tolerance of the drug is good. However, with the dosage of 150 mg/kg/day the leucocytes and erythrocytes of the peripheral blood may drop after 5--6 weeks, the