Therapeutic cytapheresis in chronic lymphocytic leukemia

✍ Scribed by G. E. Marti; T. Folks; D. L. Longo; H. Klein

• Publisher: John Wiley and Sons
• Year: 1983
• Tongue: English
• Weight: 589 KB
• Volume: 1
• Category: Article
• ISSN: 0733-2459
• DOI: 10.1002/jca.2920010408

✦ Synopsis

The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%-60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis-induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.