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ThePEA15gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes

✍ Scribed by R. Valentino; G. A. Lupoli; G. A. Raciti; F. Oriente; E. Farinaro; E. Della Valle; M. Salomone; G. Riccardi; O. Vaccaro; G. Donnarumma; G. Sesti; M. L. Hribal; M. Cardellini; C. Miele; P. Formisano; F. Beguinot

Publisher: Springer
Year: 2006
Tongue: English
Weight: 255 KB
Volume: 49
Category: Article
ISSN: 0012-186X
DOI: 10.1007/s00125-006-0455-5

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## Abstract ## Background Islet cell antibodies (ICA) represent a heterogenous group of autoantibodies to diabetes‐associated antigens, including glutamic acid decarboxylase (GAD) and the IA‐2 protein. The objectives of the present study were to compare the prevalence of autoantibodies to known bi