Theory of open-tube chromatography: an exact proof of Golay's equations

✍ Scribed by A.A. Clifford

• Book ID: 104144535
• Publisher: Elsevier Science
• Year: 1989
• Tongue: English
• Weight: 447 KB
• Volume: 471
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(00)94155-4

✦ Synopsis

A proof is given of Golay's equations for chromatography in an uncoated (or thinly coated), open-tubular column. The new derivation is exact and it is thus shown that it is not necessary to neglect some terms in the appropriate equations, as has been done in previous proofs. Furthermore, the proof is given for the situation where the rate of adsorption on to and desorption from the tube walls is not considered to be infinitely fast as was previously discussed. The effect of comparatively slow equilibration of material between the flowing medium and the tube wall is to increase the width of a peak, but not to change the average degree of retention.