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Theory and Applications of NMR-Based Screening in Pharmaceutical Research

✍ Scribed by Christopher A. Lepre; Jonathan M. Moore; Jeffrey W. Peng

Publisher
John Wiley and Sons
Year
2004
Weight
7 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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## Abstract Robust methods that monitor enzyme activity and inhibitor potency are crucial to drug discovery and development. Over the past 20 years, mass spectrometric methods have increasingly been used to measure enzyme activity and kinetics. However, for rapid screening of inhibitory compounds,