A theoretical study is presented of the catalytic mechanism of dihydrofolate reductase (DHFR) enzyme based upon the characterization of the transition structure (TS) for the hydride transfer step. Analytical gradients at AM1 and PM3 semiempirical levels have been used to characterize the saddle poin
β¦ LIBER β¦
Theoretical transition structures for hydride transfer to methyleneiminium ion from methylamine and dihydropyridine. On the nonlinearity of hydride transfers
β Scribed by Wu, Yun Dong; Houk, K. N.
- Book ID
- 126046701
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 845 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0002-7863
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