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Theoretical study of some H2-receptor agonists of histamine. The H2-essential conformation of histamine

✍ Scribed by Yves G. Smeyers; F.J. Romero-Sánchez; A. Hernández-Laguna


Book ID
119116353
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
677 KB
Volume
123
Category
Article
ISSN
0166-1280

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Theoretical study of metiamide, a histam
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The requirements for H -antagonist activity so far identified for most of 2 the known antagonists of histamine are the presence of a heterocyclic ring containing a basic center linked via a methylene chain to a substituted guanidine or thiourea polar Ž . side chain. Metiamide is a potent H antagonis