Theoretical Study of Ammonolysis of Mono
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Natalia Díaz; Dimas Suárez; Tomás L. Sordo
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Article
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2002
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John Wiley and Sons
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German
⚖ 495 KB
The ammonolysis reaction of 3-(formylamino)-4-methyl-2-oxoazetidine-1-sulfonate is investigated by quantum-chemical methods (B3LYP/6-31 G\*) as a model system of the aminolysis reaction of monobactam antibiotics involved in the allergic reaction to these drugs. The influence of the N-sulfonate group