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Theoretical study of 1,3-dipolar cycloaddition of nitrones to doubly activated nitriles

✍ Scribed by M. L. Kuznetsov; L. V. Kozlova; A. I. Dement’ev


Book ID
110180429
Publisher
SP MAIK Nauka/Interperiodica
Year
2006
Tongue
English
Weight
344 KB
Volume
51
Category
Article
ISSN
0036-0236

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1,3-Dipolar cycloadditions of prop-1-ene
✍ H. Zhang; W.H. Chan; Albert W.M. Lee; W.Y. Wong 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 142 KB

The scope and limitations of dipolar cycloaddition reactions between nitrile oxides/nitrones and prop-1-ene-1,3-sultone have been investigated. A remarkably high degree of regioselectivity and stereoselectivity was observed. The homochiral sultam 8e was synthesized in a four-step reaction sequence s