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Theoretical studies on Β-lactam antibiotics VI: Conformational analysis and structure-activity relationships of penicillin sulfoxides and cephalosporins

✍ Scribed by N. V. Joshi; V. S. R. Rao


Book ID
112828749
Publisher
Indian Academy of Sciences
Year
1982
Tongue
English
Weight
445 KB
Volume
4
Category
Article
ISSN
0250-5991

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Theoretical studies on β-lactam antibiot
✍ T. K. Vasudevan; V. S. R. Rao 📂 Article 📅 1981 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 609 KB

## Abstract Conformational‐energy calculations were carried out on the new family of β‐lactam antibiotics (viz., thienamycin, PS‐5, 1‐oxa‐ and 1‐thiapenems, and their close analogs); these exhibit broad‐spectrum antibacterial activity and stability towards β‐lactamase‐producing strains. The bicycli