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Theoretical opportunities and actual limitations of pH gradient HPLC

✍ Scribed by Roman Kaliszan; Pawel Wiczling


Book ID
105889249
Publisher
Springer
Year
2005
Tongue
English
Weight
390 KB
Volume
382
Category
Article
ISSN
1618-2650

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## Abstract A novel approach is proposed for the simultaneous optimization of mobile phase pH and gradient steepness in RP‐HPLC using artificial neural networks. By presetting the initial and final concentration of the organic solvent, a limited number of experiments with different gradient time an