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Theoretical investigation of aspects of single-molecule fluorescence detection in microcapillaries

✍ Scribed by Jörg Enderlein

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
230 KB
Volume
36
Category
Article
ISSN
0196-4763

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✦ Synopsis

In the present report, the results of a theoretical investigation of two aspects of single-molecule detection by laser-induced fluorescence in microcapillaries are presented. The two issues studied are the scattering of the exciting laser beam on the microcapillary and the change of the fluorescence lifetime of the molecule due to the electrodynamic interaction between its fluorescence emis-sion and the confining capillary. Numerical results for experimentally relevant conditions are provided.

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