✦ LIBER ✦

Theoretical Considerations on Two Equations for Estimating the Extent of Absorption After Oral Administration of Drugs

✍ Scribed by Younggil Kwon; Philip B. Inskeep

Book ID: 110344592
Publisher: Springer US
Year: 1996
Tongue: English
Weight: 604 KB
Volume: 13
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1016046004945

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effect of ‘unstirred’ water layer in the

Effect of ‘unstirred’ water layer in the intestine on the rate and extent of absorption after oral administration

✍ Win L. Chiou 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB 👁 2 views

The presence of an aqueous diffusion layer or 'unstirred' water layer adjacent to the intestinal membrane has long been regarded as a potential barrier for intestinal absorption of compounds. Theoretical analyses were performed in the present study to quantitatively determine the effect of this laye

A convenient method for estimating the q

A convenient method for estimating the quantity of drug eliminated by the routes other than hepatic metabolism and renal excretion and the fraction of drug that reaches the “first pass” after oral administration

✍ Leonid M. Berezhkovskiy 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB 👁 1 views

The comparison of routine pharmacokinetic data obtained after intravenous and oral drug administration allows to figure out that some quantity of drug, which reached the systemic circulation, was eliminated from the body by routes other than hepatic metabolism and renal excretion. This quantity is e