✦ LIBER ✦

Theoretical considerations in the calculation of bioavailability of drugs exhibiting Michaelis-Menten elimination kinetics

✍ Scribed by Gerald M. Rubin; Thomas N. Tozer

Book ID: 112473716
Publisher: Springer
Year: 1984
Tongue: English
Weight: 813 KB
Volume: 12
Category: Article
ISSN: 1573-8744
DOI: 10.1007/bf01062667

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Michaëlis - Menten Kinetics of Phenazone

Michaëlis - Menten Kinetics of Phenazone Elimination in the Perfused Pig Liver

✍ Andreasen, Per Buch ;Tønnesen, Klaus ;Rabøl, Allan ;Keiding, Susanne 📂 Article 📅 2009 🏛 Wiley (Blackwell Publishing) ⚖ 610 KB

Concurrent intravenous administration of

Concurrent intravenous administration of a labeled tracer to determine the oral bioavailability of a drug exhibiting Michaelis-Menten metabolism

✍ Gerald M. Rubin; James A. Waschek; Susan M. Pond; David J. Effeney; Thomas N. To 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 900 KB

Explicit reformulations of the LambertW-

Explicit reformulations of the LambertW-omega function for calculations of the solutions to one-compartment pharmacokinetic models with Michaelis–Menten elimination kinetics

✍ Marko Goličnik 📂 Article 📅 2011 🏛 Springer-Verlag 🌐 English ⚖ 409 KB

Improved Rearrangement of the Integrated

Improved Rearrangement of the Integrated Michaelis-Menten Equation for Calculating In Vivo Kinetics of Transport and Metabolism

✍ Russell, Richard W.; Drane, J. Wanzer 📂 Article 📅 1992 🏛 American Dairy Science Association 🌐 English ⚖ 751 KB

Theoretical analysis of the significance

Theoretical analysis of the significance of whether or not enzymes or transport systems in structured media follow Michaelis-Menten kinetics

✍ Vincent, J.C.; Thellier, M. 📂 Article 📅 1983 🏛 Biophysical Society 🌐 English ⚖ 441 KB

The influence of drug kinetics in blood

The influence of drug kinetics in blood on the calculation of oral bioavailability in linear pharmacokinetics: The traditional equation may considerably overestimate the true value

✍ Leonid M. Berezhkovskiy 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB

A common calculation of oral bioavailability is based on the comparison of the areas under the concentration-time curves after intravenous and oral drug administration. It does not take into account that after the oral dosing a drug enters the systemic circulation in different states, that is, as fr