The gas-phase basic hydrolysis of clavulanic acid (a) was studied by using the AM1 semi-empirical method. The results obtained show that the hydroxyethylidene side chain at C(2) is pivotal to the stability of the different reaction products involved. The products with an open oxazolidine ring are mo
Theoretical calculations of β-lactam antibiotics
✍ Scribed by J. Frau; J. Donoso; B. Vilanova; F. Muñoz; F. García Blanco
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 597 KB
- Volume
- 86
- Category
- Article
- ISSN
- 1432-2234
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