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Theoretical and Synthetic Approach to Novel Spiroheterocycles Derived from Isatin Derivatives and L-Proline via 1,3-Dipolar Cycloaddition.

✍ Scribed by R. T. Pardasani; P. Pardasani; V. Chaturvedi; S. K. Yadav; A. Saxena; I. Sharma


Publisher
John Wiley and Sons
Year
2003
Weight
102 KB
Volume
34
Category
Article
ISSN
0931-7597

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Theoretical and synthetic approach to no
✍ R. T. Pardasani; P. Pardasani; V. Chaturvedi; S. K. Yadav; A. Saxena; I. Sharma πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 117 KB

## Abstract A cyclic secondary α‐amino acid, viz. L‐proline, reacts with isatin derivatives via decarboxylative azomethine ylide formation and subsequent cycloaddition with various dipolarophiles to give cycloadducts in moderate to good yield. Theoretical studies have been performed to study the st