Theoretical and experimental epitope mapping of thymosin β4
✍ Scribed by S. Becker; F.P. Armbruster; B. Müller; H. Echner; A. Kapurnotu; E. Livaniou; M. Mihelić; S. Stoeva; W. Voelter
- Book ID
- 118903024
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 627 KB
- Volume
- 177
- Category
- Article
- ISSN
- 0022-1759
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📜 SIMILAR VOLUMES
Thymosin [}4 is a major actin sequestering peptide in vertebrate cells and plays a role in the regulation of actin monomer/polymer ratio. Thymosin [}9 and thymosin [}9 et are minor variants of thymosin [}4. The possible function of these peptides has been investigated by comparing the actin binding
## Abstract The total synthesis of thymosin β~4~ by means of classical methods using three protected fragments is described. For their syntheses the Z/__t__Bu strategy and temporary phenyl ester protection of the C‐terminal carboxyl were used. Various coupling procedures were applied in order to op