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Theoretical analysis of the possible mechanisms of interferon induction for priming and blocking

โœ Scribed by S. I. Bazhan; V. A. Likhoshvai; O. E. Belova

Book ID
104954780
Publisher
Springer US
Year
1993
Tongue
English
Weight
611 KB
Volume
116
Category
Article
ISSN
0007-4888

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Theoretical analysis of the regulation o
Theoretical analysis of the regulation of interferon expression during priming and blocking
โœ S.I. Bazhan; V.A. Likhoshvai; O.E. Belova ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 591 KB

Interferon superinduction, in the case of cell pretreatment with low doses of interferon (priming), may be explained by activation of 2',5'-oligoadenylate synthetase and endonuclease L, since the latter, as expected, leads to a more rapid amplification of the standard scheme of interferon induction