𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the thymidylate synthase reaction

✍ Scribed by Giulio Rasttelli; Maria Paola Costi


Book ID
113258909
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
643 KB
Volume
343
Category
Article
ISSN
0166-1280

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Chemical modelling of the thymidylate sy
✍ Paul F.C. van der Meij; Upendra K. Pandit πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 258 KB

The intramolecular thiol addition to C(6) in 1-(3-mercaptopropyl)-5-aminomethyluracil derivatives in protic media leads to the formation of bicyclic 5,6\_dihydrouracil derivatives, which may be regarded as models of the covalent ternary complex in the thymidylate synthase reaction. Evidence is prese