Thec-ets-1Proto-oncogene Is a New Early-Response Gene Differentially Regulated by Cytokines and Growth Factors in Human Fibroblasts

Induction of early growth response-1 gen

Induction of early growth response-1 gene by interleukin-1β and tumor necrosis factor-α in normal human bone marrow stromal and osteoblastic cells: regulation by a protein kinase C inhibitor

✍ Lala R. Chaudhary; Su-Li Cheng; Louis V. Avioli 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 706 KB

The early growth response-1 (Egr-1) gene has been identified as a nuclear transcriptional factor and implicated in the regulation of growth and differentiation of osteoblastic cells. In the present study, we investigated whether Egr-1 mRNA is expressed and induced by interleukin-1 beta, (IL-beta) an