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The γ-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy

✍ Scribed by Stuart E. Smith; Naila S. Parvez; Astrid G. Chapman; Brian S. Meldrum


Book ID
115889192
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
657 KB
Volume
273
Category
Article
ISSN
0014-2999

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Temporal lobe epilepsy (TLE) is one of the most commonly occurring and most intractable forms of seizure disorders in humans. The fundamental mechanisms underlying the pathogenesis of the disorder have, however, not yet been elucidated. El is an inbred mouse strain with genetic predisposition to epi