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The β5‘ Loop of the Pancreatic Lipase C2-like Domain Plays a Critical Role in the Lipase−Lipid Interactions †

✍ Scribed by Chahinian, Henri; Bezzine, Sofiane; Ferrato, Francine; Ivanova, Margarita G.; Perez, Barbara; Lowe, Mark E.; Carrière, Frédéric


Book ID
126973495
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
183 KB
Volume
41
Category
Article
ISSN
0006-2960

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The role of pancreatic lipase C2-like do
✍ Henri Chahinian; Valérie Belle; André Fournel; Frédéric Carrière 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 530 KB

## Abstract Human pancreatic lipase (HPL) consists of two functional domains: an N‐terminal catalytic domain (N‐HPL), and a β‐sandwich C‐terminal domain (C‐HPL) involved in the binding process between HPL and colipase. Structural similarities between C‐HPL and C2 domains have suggested another func