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The β3-Adrenergic System and β3-Adrenergic Agonists

✍ Scribed by Jonathan R. S. Arch

Book ID
110304702
Publisher
Springer
Year
2001
Tongue
English
Weight
324 KB
Volume
2
Category
Article
ISSN
1389-9155

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The synthesis of b 3 -adrenergic receptor agonists A and B with radiolabeled amide fragment, required for drug disposition studies, was accomplished based on initial formation of 2-(4-(2-amino-2-methylpropyl)phenoxy)-5-[ 14 C]-cyanopyridine by the reaction of 2-bromo-5-iodopyridine with para-substit