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The α2 and α5 integrin genes: identification of transcription factors that regulate promoter activity in epidermal keratinocytes

✍ Scribed by Angel L Corbi; Uffe Birk Jensen; Fiona M Watt

Book ID: 117101884
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 331 KB
Volume: 474
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(00)01591-x

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## Abstract The α3β1 integrin is an adhesion receptor for extracellular matrix proteins, including laminin isoforms, and plays crucial roles in the organization of epithelial and endothelial tissues. The aberrant expression of this adhesion molecule on tumor cells is associated with their invasive