The zwitterion structure of imidazol-1-ylacetic acids in the solid state and in solution
✍ Scribed by Pilar López; Paula Zaderenko; Jose Luis Balcazar; Isabel Fonseca; Félix Hernández Cano; Paloma Ballesteros
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 564 KB
- Volume
- 377
- Category
- Article
- ISSN
- 0022-2860
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## Abstract The structure of the hypoglycemic agent Gliclazide has been studied by ^1^H, ^13^C, and ^15^N NMR in solution (CDCl~3~ and DMSO‐__d__~6~) and in the solid state. In the solid state, the compound crystallizes as an __EZ__ isomer without dynamic properties. In CDCl~3~ solution, the struct