The purpose and methodology of a 4-year longitudinal study based on a cohort aged 20 years are presented. A two-stage procedure was chosen; in 1978, 2201 males and 2346 females, aged 19-20, were examined. This sample was representative of the respective age group in the Canton of Zurich. From high a
The Zurich study —A prospective epidemiological study of depressive, neurotic and psychosomatic syndromes
✍ Scribed by J. Angst; A. Dobler-Mikola
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 707 KB
- Volume
- 234
- Category
- Article
- ISSN
- 1433-8491
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✦ Synopsis
How common and how significant are brief depressive episodes (BDE) lasting less than 2 weeks? The authors propose splitting the BDE into two groups: one occurring monthly over 1 year of observation, termed 'recurrent brief depression' (RBD), and those occurring less frequently, labeled 'nonrecurrent brief depression' (NRBD) From a medical point of view, the RBD are a relevant group Different thresholds of definition are tested, the narrowest of which (including occupational impairment and predetermined minimum number of symptoms) is accepted for 'case'-definition The such defined RBD (SYM) group differs from major depression only by length and frequency of episodes In a young cohort, its 1-year prevalence rate was found to be 4 4 % (males 3 9 %, females 4 9 %) One-third of these cases needed treatment, a fourth suffered from pronounced subjective and social impairment as well as from persistent suicidal ideation The selfreporting of subjective impairment, assessed with the SCL-90 symptom inventory and an analog-rating, yields high scores which are in no way inferior to major depression diagnosed with RDC, DSM-III or EDE (SYM) criteria The RBD (SYM) demonstrate less hypomania than the major depressive disorders On the other hand, a family history of depression is equally frequent across all groups The validity of the RBD(SYM) group has yet to be confirmed by a follow-up study, and further research is needed to delineate it from secondary depression.
The findings largely support the hypothesis of a continuum from mild and short to more severe, longer lasting depressive syndromes, but they do not exclude heterogeneity of RBD (Angst and Dobler-Mikola 1984 b).
The diagnostic concept of the RBD and the 'dysthymic disorders' of DSM-III are discussed The similarity between RBD (SYM) and major depression questions the validity of the 2-week duration criterion.
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