The Zn-finger GATA transcription factor is important for migration and essential for proliferation of the heart progenitor cells in Ciona intestinalis

Expression of the transcription factor G

Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus

✍ Rudolf W. Hendriks; Martijn C. Nawijn; J. Douglas Engel; Hikke van Doorninck; Fr 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 3 views

GATA-3 is a zinc-finger transcription factor that is essential for both early T cell development and Th2 cell differentiation. To quantify GATA-3 expression during T cell development in vivo in the mouse, the GATA-3 gene was targeted by insertion of a lacZ reporter by homologous recombination in emb