The X-gene of human hepatitis B virus transactivates the c-jun and α-fetoprotein genes
✍ Scribed by M. X. Zhou; M. Watabe; K. Watabe
- Publisher
- Springer Vienna
- Year
- 1994
- Tongue
- English
- Weight
- 855 KB
- Volume
- 134
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Human hepatocytes infected by hepatitis B virus (HBV) produce the proinflammatory cytokine, tumor necrosis factor (TNF-). In this study, we explored the mechanism of induction of TNF- synthesis by HBV. We found that the stable HBV-transfected hepatoma cell line, 2. 2.15, expressed high-molecular-wei
lacZ gene driven by the b-actin -based promoter. Ex-SEE EDITORIAL ON PAGE 1696. pression of the HSVtk gene by adenovirus from AFP promoter/enhancer (AdAFPtk) induced the cells sensitive to ganciclovir (GCV) in the AFP-producing cell We have developed a recombinant replication-deline efficiently, but
For an approach of gene therapy for hepatocellular carcinoma (HCC), transcriptional regulatory sequence (TRS) of either alpha-fetoprotein (AFP) or albumin has been used for targeting cancer cells. To examine the feasibility of using TRSs of these genes for possible gene therapy of HCCs, the cellular