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The w/w+ SMART assay of Drosophila melanogaster detects the genotoxic effects of reactive oxygen species inducing compounds

✍ Scribed by Isabel Gaivão; L.Maria Sierra; Miguel A Comendador

Book ID
117767775
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
74 KB
Volume
440
Category
Article
ISSN
1383-5718

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Biotransformation of several structurally related 2B compounds to reactive metabolites was evaluated in the somatic w/w+ assay of Drosophila melanogaster. Chemicals tested were the dichlorinated alkanes dichloromethane (DCM), 1,2-dichloroethane (DCE), and 1,3-dichloropropane (DCP); the thiouracil de