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The Wnt signaling pathway: Aging gracefully as a protectionist?

✍ Scribed by Kenneth Maiese; Faqi Li; Zhao Zhong Chong; Yan Chen Shang


Book ID
113845867
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
907 KB
Volume
118
Category
Article
ISSN
0163-7258

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## Abstract Identification of Pygopus in __Drosophila__ as a dedicated component of the Wg (fly homolog of mammalian Wnt) signaling cascade initiated many inquiries into the mechanism of its function. Surprisingly, the nearly exclusive role for Pygopus in Wg signal transduction in flies is not seen