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The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death

✍ Scribed by Grotewold, L.


Book ID
111749203
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
324 KB
Volume
21
Category
Article
ISSN
0261-4189

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## Abstract Bone morphogenetic proteins (BMPs) have been shown to regulate both osteoblasts and osteoclasts. We previously reported that BMP2 could directly enhance RANKL‐mediated osteoclast differentiation by increasing the size and number of osteoclasts. Similarly, genetic deletion of the BMP ant