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The White Rat in the Biological Assay of Senna and Its Preparations

โœ Scribed by Vincent, Hugh C. ;Waldon, C.H. ;Lee, C.O.


Publisher
Elsevier
Year
1945
Weight
291 KB
Volume
34
Category
Article
ISSN
0095-9553

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The intestinal metabolism of N-acetylcysteine was studied in the rat. Isolated intestinal e ithelial cells were shown to rapdily deacetylate [ ''C]-N-acetylcysteine to [&I-cysteine, with slight oxidation of the latter to disulfide species. The cells did not accumulate reduced or oxidized cysteine, a