Induction of the von Hippel-Lindau tumor
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Jörn Karhausen; Tianqing Kong; Sailaja Narravula; Sean P. Colgan
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Article
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2005
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John Wiley and Sons
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English
⚖ 251 KB
## Abstract Hypoxia–inducible factor (HIF) remains the central focus of oxygen sensing during hypoxia. HIF is a heterodimeric transcription factor consisting of an oxygen‐regulated alpha‐ and a constitutively expressed beta subunit. The von Hippel‐Lindau tumor suppressor (pVHL) is a component of th