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The vitamin D analogue BXL-628 inhibits growth factor-stimulated proliferation and invasion of DU145 prostate cancer cells

✍ Scribed by Sara Marchiani; Lorella Bonaccorsi; Pietro Ferruzzi; Clara Crescioli; Monica Muratori; Luciano Adorini; Gianni Forti; Mario Maggi; Elisabetta Baldi

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
309 KB
Volume
132
Category
Article
ISSN
1432-1335

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## Abstract The epidermal growth factor (EGF) plays a role in the development of prostate cancer, which becomes essential after androgen resistance has emerged. The EGF receptor (EGFR) is therefore a potential target for anticancer therapy. We evaluated the effects of ZD1839 (β€˜Iressa’), an orally a