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The virological and clinical significance of mutations in the overlapping envelope and polymerase genes of hepatitis B virus

✍ Scribed by Joseph Torresi

Book ID: 117769568
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 318 KB
Volume: 25
Category: Article
ISSN: 1386-6532
DOI: 10.1016/s1386-6532(02)00049-5

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## Abstract Lamivudine results in the selection of resistant hepatitis B virus (HBV) variants. Because the surface gene of HBV overlaps completely the polymerase gene, the incidence and profile of surface and polymerase gene mutations were investigated prospectively in chronic HBV patients who were