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The vascular endothelial growth factor receptor KDR/Flk-1 is a major regulator of malignant ascites formation in the mouse hepatocellular carcinoma model

✍ Scribed by Hitoshi Yoshiji; Shigeki Kuriyama; Daniel J. Hicklin; James Huber; Junichi Yoshii; Yasuhide Ikenaka; Ryuichi Noguchi; Toshiya Nakatani; Hirohisa Tsujinoue; Hiroshi Fukui


Book ID
111721460
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
301 KB
Volume
33
Category
Article
ISSN
0270-9139

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KDR/Flk-1 is a major regulator of vascul
✍ Hitoshi Yoshiji; Shigeki Kuriyama; Daniel J. Hicklin; James Huber; Junichi Yoshi πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 375 KB πŸ‘ 1 views

Vascular endothelial growth factor (VEGF), which is one of the most potent angiogenic factors, has been shown to play a pivotal role in tumor angiogenesis, including hepatocellular carcinoma (HCC). The effects of VEGF are mediated mainly through two distinct receptors, flt-1 and KDR/ Flk-1. It has b