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The variability of the mitochondrial genome in human aging: a key for life and death?

✍ Scribed by G. Rose; G. Passarino; C. Franceschi; G. De Benedictis

Book ID
117755850
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
342 KB
Volume
34
Category
Article
ISSN
1357-2725

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Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomi