The value of molecular genetic analysis in the diagnosis and prognosis of renal cell tumours
β Scribed by G. Kovacs
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 630 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0724-4983
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Very frequent loss of heterozygosity (LOH) on chromosome 3p has been found in human renal cell carcinoma (RCC). In the present study, we examined LOH at the retinoblastoma (RB), mutated in colorectal cancer (MCC) and adenomatous polyposis coli (APC) tumour suppressor genes loci, and mutations of the
## Abstract ## BACKGROUND The American Joint Committee on Cancer and the Union Internationale Contre le Cancer have acknowledged routine laboratory parameters, such as serum calcium, alkaline phosphatase, hemoglobin, and the erythrocyte sedimentation rate (ESR), as predictors of survival in patien