Continuous vincristine infusion as part
โ
C. R. Pinkerton; B. McDermott; T. Philip; P. Biron; C. Ardiet; H. Vandenberg; M.
๐
Article
๐
1988
๐
Springer
๐
English
โ 442 KB
A 5-day continuous infusion of vincristine (VCR; total dose 4 mg/m2) has been given as part of a high-dose chemoradiotherapy regimen with bone marrow transplantation. Evidence of neurotoxicity, such as weakness, paraesthesia and intestinal hypomotility, was evaluated prospectively in nine patients.