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The value of an expert system in performing clinical drug trials

✍ Scribed by Willem R.M. Dassen; Rob Mulleneers; Herman L.L. Frank

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
467 KB
Volume
21
Category
Article
ISSN
0010-4825

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✦ Synopsis

An expert system has been designed to assist the cardiologist in determining whether patients can be included in clinical trials. This system contains knowledge on inclusion and exclusion criteria for six drug trials, and has been validated in 100 randomly selected patients. In 97 cases, the expert system and the cardiologist made an identical classification; in the remaining three cases, the patient was incorrectly classified by the physician. The system will also optimize the order in which questions are asked in order to minimize the time required to decide on inclusion or exclusion.

Expert system

Drug thials Decision support

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## Abstract A consensus conference on the topic of clinical drug trials in cognitive disorders of the elderly was held in Marseille on January 28–29, 1993. At the end of this conference, several recommendations were made. Drugs used in trials must be chosen according to solid neurobiological eviden