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The validity and ethics of giving placebo in a randomized nonpharmacologic trial was evaluated

โœ Scribed by M.G. Spigt; P.G. Knipschild; C.P. van Schayck; J.A. Knottnerus


Book ID
116622609
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
214 KB
Volume
58
Category
Article
ISSN
0895-4356

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The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the tr