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The utility of short-term tests for mutagenicity

โœ Scribed by Frederick J. De Serres


Book ID
119091685
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
127 KB
Volume
38
Category
Article
ISSN
0165-1161

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Utility of short-term tests for genetic
โœ David M. DeMarini; Joellen Lewtas; Herman E. Brockman ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 840 KB

By definition, short-term tests (STTs) for genetic toxicity detect genotoxic agents, not carcinogens specifically. However, there is sufficient evidence, based on mechanistic considerations alone, to say that genotoxic agents are potential carcinogens. STTs have high statistical power, are almost al