๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The use of the simplex method for the optimisation of non-linear functions on a laboratory microcomputer

โœ Scribed by R. Nicol; P. Smith; P.R. Raggatt


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
660 KB
Volume
16
Category
Article
ISSN
0010-4825

No coin nor oath required. For personal study only.

โœฆ Synopsis


The use of the microcomputer

for the processing of analytical data in the laboratory is currently increasing. However, computational methods which have been used successfully on minicomputers may not be suitable for microcomputer implementation due to the lack of available precision. This paper describes a technique, namely the simplex method, which may be successfully applied to the processing of laboratory data on an 8-bit microcomputer.

The method is used to optimise a non-linear function in order to fit a curve to radioimmunoassay (RIA) and immunoradiometricassay (IRMA) data. The microcomputer package described has been tested on laboratory data and is currently in use in a clinical biochemistry laboratory.

Simplex method Non-linear curve fitting Radioimmunoassay Laboratory data processing Clinical biochemistry Immunoradiometricassay


๐Ÿ“œ SIMILAR VOLUMES


Use of a microcomputer for the definitio
โœ D. Coomans; I. Broeckaert; M.P. Derde; A. Tassin; D.L. Massart; S. Wold ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 727 KB

The use of multivariate confidence regions is proposed for the classification of clinical laboratory profiles into diagnostic classes. For this purpose, a multivariate confidence region is developed for each diagnostic class. Three methods (UNEQ, EQ, and SIMCA) are evaluated and compared with classi