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The use of the Congo red-related dye DBACR to recognize the heavy chain-derived abnormality of myeloma immunoglobulins

✍ Scribed by Paweł Spólnik; Leszek Konieczny; Barbara Piekarska; Janina Rybarska; Barbara Stopa; Grzegorz Zemanek; Anna Drozd; Marcin Król; Irena Roterman; Teresa Wolska-Smoleń; Aleksander B. Skotnicki


Publisher
Springer
Year
2006
Tongue
English
Weight
814 KB
Volume
54
Category
Article
ISSN
0004-069X

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An approach to understand the complexati
✍ Marcin Król; Irena Roterman; Barbara Piekarska; Leszek Konieczny; Janina Rybarsk 📂 Article 📅 2005 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 265 KB 👁 1 views

## Abstract Congo red, a dye of high self‐assembling tendency, has been found to form complexes with proteins by adhesion of the ribbon‐like supramolecular ligand to polypeptide chains of β‐conformation. Complexation is allowed by local or global protein instability, facilitating penetration of the