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The use of the APL360 system in pharmacology. A computer assisted analysis of efflux data

✍ Scribed by David A. Cook; Grahame S. Taylor

Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
578 KB
Volume
4
Category
Article
ISSN
0010-4809

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✦ Synopsis

The APL\360 system has been employed to provide a convenient and objective technique for the analysis of data from experiments involving the efflux of a radioactive tracer from a biological preparation. The programmes employ uncorrected data from scintillation or gas-flow counting of samples of the medium into which tracer was released, and provide data concerning compartment sizes, rate constants and half times using a simple peeling technique. Data are also made available concerning parameters of the rate of tracer efflux, the efflux coefficient, the logarithmic plot of rate of efflux against tissue desaturation and the compartment sizes in terms of moles of tracer per kilogramme of material. The use of this function has greatly facilitated the routine analysis of data from experiments of the type described.

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