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The Use of Scintigraphy to Provide 'Proof of Concept' for Novel Polysaccharide Preparations Designed for Colonic Drug Delivery

โœ Scribed by Dawn A. Adkin; Carole J. Kenyon; E. Itzhack Lerner; Isaac Landau; Eric Strauss; David Caron; Adel Penhasi; Abraham Rubinstein; Ian R. Wilding

Book ID
110308668
Publisher
Springer US
Year
1997
Tongue
English
Weight
413 KB
Volume
14
Category
Article
ISSN
0724-8741

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Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous dispersion (aqueous), or Eudragit FS aqueous dispersion. Eight fasted volunt